Program Director, Center for Regenerative Sports MedicineProgram Director, Center for Regenerative Sports Medicine, Steadman Philippon Research Institute
My research focuses on developing novel stem cell based therapies for the treatment of musculoskeletal diseases and injuries. Specifically, I believe we can drive improved tissue regeneration by recapitulating the developmental and repair sequences stem cells follow. I utilize a cross-disciplinary approach that combines engineering training in biologically modified synthetic polymers, cell and developmental biology, and pre-clinical models of orthopaedic injuries. In previous studies, I used mesenchymal stem cells (MSCs) to promote regeneration of both articular cartilage and bone. Recently we have validated a paradigm-shifting approach to bone regeneration through a cartilage intermediate using a murine model of a segmental defect. With this application we hope to test strategies for clinical translation of our preclinical data and receive mentorship associated with the bench-to-bedside development.